Solid lipid nanoparticles for ocular drug delivery

  title={Solid lipid nanoparticles for ocular drug delivery},
  author={Ali Seyfoddin and John P. Shaw and Raida S Al-Kassas},
  journal={Drug Delivery},
  pages={467 - 489}
Ocular drug delivery remains challenging because of the complex nature and structure of the eye. Conventional systems, such as eye drops and ointments, are inefficient, whereas systemic administration requires high doses resulting in significant toxicity. There is a need to develop novel drug delivery carriers capable of increasing ocular bioavailability and decreasing both local and systemic cytotoxicity. Nanotechnology is expected to revolutionize ocular drug delivery. Many nano-structured… 

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