Solid lipid nanoparticles as delivery systems for Gambogenic acid.

  title={Solid lipid nanoparticles as delivery systems for Gambogenic acid.},
  author={Xia Huang and Yan-jie Chen and Dai-yin Peng and Qing-lin Li and Xiao-shan Wang and Dian-lei Wang and Weidong Chen},
  journal={Colloids and surfaces. B, Biointerfaces},
In this study, Gambogenic acid loaded by solid lipid nanoparticles (GNA-SLNs) was explored to reduce toxicity and improve therapeutic efficacy. GNA-SLNs were prepared by emulsification and low temperature solidification methods, and the freeze-dried powders were then developed to improve the stability. The physical-chemical properties of the products in terms of particle size, zeta potential, morphology and entrapment efficiency were well evaluated. The results revealed that the mean diameter… CONTINUE READING


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