Solid‐Phase Synthesis of Fluorinated Analogues of Glycosyl 1‐Phosphate Repeating Structures from Leishmania using the Phosphoramidite Method

@inproceedings{Hara2018SolidPhaseSO,
  title={Solid‐Phase Synthesis of Fluorinated Analogues of Glycosyl 1‐Phosphate Repeating Structures from Leishmania using the Phosphoramidite Method},
  author={Rintaro Iwata Hara and Aya Yaoita and Katsuya Takeda and Hiroaki Ueki and Ayumu Ishii and Hideyuki Imoto and Satoshi Kobayashi and Michi Sano and Mihoko Noro and Kazuki Sato and Takeshi Wada},
  booktitle={ChemistryOpen},
  year={2018}
}
Bacterial and protozoan sugar chains contain glycosyl 1-phosphate repeating structures; these repeating structures have been studied for vaccine development. The fluorinated analogues of [β-Gal-(1→4)-α-Man-(1→6)-P-] n , which are glycosyl 1-phosphate repeating structures found in Leishmania, were synthesised using the solid-phase phosphoramidite method… CONTINUE READING