Solasodine glycosides . Selective cytotoxicity for cancer cells and inhibition of cytotoxicity by rhamnose in mice with sarcoma 180

@inproceedings{Chama2003SolasodineG,
  title={Solasodine glycosides . Selective cytotoxicity for cancer cells and inhibition of cytotoxicity by rhamnose in mice with sarcoma 180},
  author={B. E. Chama and B. Daunterb},
  year={2003}
}
  • B. E. Chama, B. Daunterb
  • Published 2003
BEC, a standard mixture of so~~odine glycosides is effective in vivo against murine sarcoma 180 (SZ80), whereas the aglycone solasodine at equimolar concentrations is ineffective. The efficacy of BEC against Sl80 in uiuo can be inhibited by rhamnose. Mice which are in their terminal stage with Sl80 can tolerate and become symptom-free of cancer by single dose administration of BEC at concentrations of BEC three times the LD,, for normal mice. These observations suggest that the binding of… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 10 references

Topical treatment of pre-malignant and malignant skin cancers with curaderm

  • B. E. Cham, B. Daunter
  • Drugs Today
  • 1990

Curaderm (antineoplastic) launched in Australia

  • B. E. Cham, B. Daunter
  • Drug News Perspect ,
  • 1989

Monograph on BEC

  • B. E. Cham
  • Drugs Future
  • 1988

Anti - tumour effects of glycoalkaioids isolated from solanum sodomaeum

  • E. Cham.B., M. Gilliver, L. Wilson
  • Planta Medica
  • 1987

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