Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared to 8-methoxypsoralen and 5-methoxypsoralen.

@article{Schempp2006SolarSP,
  title={Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared to 8-methoxypsoralen and 5-methoxypsoralen.},
  author={Christoph Mathis Schempp and Birgit Simon-Haarhaus and Richard Krieger and Jan C. Simon},
  journal={Planta medica},
  year={2006},
  volume={72 10},
  pages={941-3}
}
Dictamnine, a furoquinoline alkaloid of the Rutaceae plant family, has been shown to be mutagenic and phototoxic in bacteria and yeasts. Here, we have investigated the phototoxic effect of dictamnine in human Jurkat T cells and HaCaT keratinocytes. Dictamnine was isolated from the roots of DICTAMNUS ALBA L. and was photoactivated with solar simulated… CONTINUE READING