Sofpironium Bromide: First Approval

@article{Paik2020SofpironiumBF,
  title={Sofpironium Bromide: First Approval},
  author={Julia Paik},
  journal={Drugs},
  year={2020},
  volume={80},
  pages={1981 - 1986}
}
  • J. Paik
  • Published 24 November 2020
  • Biology
  • Drugs
Sofpironium bromide (ECCLOCK® in Japan) gel is a topical anticholinergic agent developed by Bodor Laboratories and licenced to Brickell Biotech for the treatment of hyperhidrosis. The drug is designed to reduce sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. In September 2020, sofpironium bromide gel 5% received its first approval in Japan for the treatment of primary axillary hyperhidrosis (PAH). Clinical studies are currently ongoing in the USA to… 
4 Citations
Sofpironium bromide: an investigational agent for the treatment of axillary hyperhidrosis
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Topical anticholinergic medications for primary hyperhidrosis: A protocol for systematic review and meta-analysis
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Evaluating systemic and topical safety and tolerability of topical application of anticholinergics for PHH and analysis of evidence for the efficacy and toleration is limited.
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