Sofosbuvir plus simeprevir for the treatment of genotype 1 chronic hepatitis C: a review of evidence.


INTRODUCTION Sofosbuvir (SOF) with simeprevir (SIM) combination was the first interferon-free regimen that reached optimal results in terms of sustained viral response (SVR). Areas covered: A systematic review of the scientific literature concerning the effects that the SOF/SIM combination had on hepatitis C genotype 1 patients yielded 771 references. After… (More)