Sodium tanshinone IIA sulfonate inhibits canonical transient receptor potential expression in pulmonary arterial smooth muscle from pulmonary hypertensive rats.

@article{Wang2013SodiumTI,
  title={Sodium tanshinone IIA sulfonate inhibits canonical transient receptor potential expression in pulmonary arterial smooth muscle from pulmonary hypertensive rats.},
  author={Jian Wang and Qian Jiang and Limei Wan and Kai Yang and Yi Zhang and Yuqin Chen and Elizabeth Ottenberg Wang and Ning Lai and Lei Zhao and Hua Jiang and Yueqian Sun and Nan-shan Zhong and Pixin Ran and Wenju Lu},
  journal={American journal of respiratory cell and molecular biology},
  year={2013},
  volume={48 1},
  pages={125-34}
}
Danshen, the dried root of Salvia miltiorrhiza, is widely used in clinics in China for treating various diseases, including cardiovascular diseases. Sodium tanshinone IIA sulfonate (STS), a water-soluble derivative of tanshinone IIA isolated as the major active component from Danshen, was recently reported to be effective in attenuating the characteristic pulmonary vascular changes associated with chronically hypoxic pulmonary hypertension (CHPH); however, the underlying detailed mechanisms are… CONTINUE READING
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