Sodium oxybate for the treatment of fibromyalgia
@article{Staud2011SodiumOF, title={Sodium oxybate for the treatment of fibromyalgia}, author={R. Staud}, journal={Expert Opinion on Pharmacotherapy}, year={2011}, volume={12}, pages={1789 - 1798} }
Introduction: Gamma-hydroxybutyrate (GHB) is a short-chain fatty acid that is synthesized within the CNS, mostly from its parent compound gamma amino butyric acid (GABA). GHB acts as a neuromodulator/neurotransmitter to affect neuronal activity of other neurotransmitters and so, stimulate the release of growth hormone. Its sodium salt (sodium oxybate: SXB) was approved by the Food and Drug Administration (FDA) for the treatment of narcolepsy. SXB has shown to improve disrupted sleep and… CONTINUE READING
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References
SHOWING 1-10 OF 110 REFERENCES
gamma-Hydroxybutyrate/sodium oxybate: neurobiology, and impact on sleep and wakefulness.
- Medicine
- CNS drugs
- 2006
- 57
The effects of sodium oxybate on clinical symptoms and sleep patterns in patients with fibromyalgia.
- Medicine
- The Journal of rheumatology
- 2003
- 194
- Highly Influential
The treatment of narcolepsy-cataplexy with nocturnal gamma-hydroxybutyrate.
- Medicine
- The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
- 1979
- 145
- PDF
Flumazenil effects on growth hormone response to gamma‐hydroxybutyric acid
- Psychology, Medicine
- International clinical psychopharmacology
- 1994
- 45
Gamma-hydroxybutyrate (GHB) in humans: pharmacodynamics and pharmacokinetics.
- Medicine
- Annals of the New York Academy of Sciences
- 2006
- 53
The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial
- Medicine
- Anesthesia and analgesia
- 2010
- 172
- PDF