Sodium ion modulates collagen types in human fibroblastic cells in culture.

@article{Hata1983SodiumIM,
  title={Sodium ion modulates collagen types in human fibroblastic cells in culture.},
  author={Ryu-ichiro Hata and H Sunada and Yoshio Nagai},
  journal={Biochemical and biophysical research communications},
  year={1983},
  volume={117 1},
  pages={313-8}
}
Collagen synthesis in human fibroblasts was increased by the presence of 0.1M excess NaCl in the culture medium. Type analysis of the collagen produced by the cells showed the increase in the ratio of type III collagen to the total collagen. Similar NaCl effects were observed in several cell lines derived from different tissues. Sodium ion but not chlorine… CONTINUE READING