Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy.

@article{krti2015SodiumglucoseCI,
  title={Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy.},
  author={Marko {\vS}krti{\'c} and David Z I Cherney},
  journal={Current opinion in nephrology and hypertension},
  year={2015},
  volume={24 1},
  pages={96-103}
}
PURPOSE OF REVIEW Renal hyperfiltration has been used as a surrogate marker for increased intraglomerular pressure in patients with diabetes mellitus. Previous human investigation examining the pathogenesis of hyperfiltration has focused on the role of neurohormones such as the renin-angiotensin-aldosterone system (RAAS). Unfortunately, RAAS blockade does… CONTINUE READING