Sodium fluoride dissolution of human calcium oxalate/phosphate stone particles.

  title={Sodium fluoride dissolution of human calcium oxalate/phosphate stone particles.},
  author={Roger K. Low and Sunita P. Ho and Marshall L. Stoller},
  journal={Journal of endourology},
  volume={9 5},
The dissolutive effects of sodium fluoride on human calcium stone particles were investigated in an in vitro model. Stone particles composed of 65% calcium oxalate and 35% calcium phosphate dissolved in a dose-dependent fashion with NaF exposure. Stone particles exposed to 60 mM NaF had a 17% reduction in particle mass after 24 hours and a 62% reduction after 7 days in comparison with experimental controls bathed in physiologic normal saline. The systemic toxicity of the dose of oral fluoride… 

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