Sodium fluoride causes oxidative stress and apoptosis in the mouse liver

@inproceedings{Lu2017SodiumFC,
  title={Sodium fluoride causes oxidative stress and apoptosis in the mouse liver},
  author={Yujiao Lu and Qin Luo and Hengmin Cui and Huidan Deng and Ping Kuang and Huan Liu and Jing Fang and Zhicai Zuo and Junliang Deng and Yinglun Li and Xun Wang and Ling Zhao},
  booktitle={Aging},
  year={2017}
}
The current study was conducted to investigate the effect of sodium fluoride (NaF) on the oxidative stress and apoptosis as well as their relationship in the mouse liver by using methods of flow cytometry, quantitative real-time polymerase chain reaction (qRT-PCR), western blot, biochemistry and experimental pathology. 240 four-week-old ICR mice were randomly divided into 4 groups and exposed to different concentration of NaF (0 mg/kg, 12 mg/kg, 24 mg/kg and 48 mg/kg) for a period of 42 days… CONTINUE READING