Sodium-dependent phosphate cotransporters and vascular calcification.

  title={Sodium-dependent phosphate cotransporters and vascular calcification.},
  author={Xianwu Li and Cecilia M. Giachelli},
  journal={Current opinion in nephrology and hypertension},
  volume={16 4},
PURPOSE OF REVIEW Vascular calcification is associated with cardiovascular events in patients with end-stage renal disease and diabetes. Hyperphosphatemia is a risk factor for vascular calcification in these patients. Sodium-dependent phosphate cotransporters are required for cellular phosphate uptake. This review focuses on the potential role of phosphate transport and type III sodium-dependent phosphate cotransporters in the process of vascular calcification. RECENT FINDINGS Consistent with… CONTINUE READING


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