Sodium-coupled transporters for Krebs cycle intermediates.

  title={Sodium-coupled transporters for Krebs cycle intermediates.},
  author={Ana M Pajor},
  journal={Annual review of physiology},
  • Ana M Pajor
  • Published 1999 in Annual review of physiology
Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate are transferred across plasma membranes of cells by secondary active transporters that couple the downhill movement of sodium to the concentrative uptake of substrate. Several transporters have been identified in isolated membrane vesicles and cells based on their functional properties, suggesting the existence of at least three or more Na+/dicarboxylate cotransporter proteins in a given species. Recently, several… CONTINUE READING


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