Sodium channels accumulate at the tips of injured axons.


The axolemmal distribution of voltage-gated sodium channels largely determines the regions of axonal electrical excitability. Using a well-characterized anti-sodium channel antibody, we examined peripheral nerve fibers focally injured by exposure to the neurotoxic agent, potassium tellurite (K2TeO3). Immunocytochemical and radioimmunoassay data showed a… (More)


Cite this paper

@article{England1994SodiumCA, title={Sodium channels accumulate at the tips of injured axons.}, author={John D F England and Fabia Gamboni and Melanie A Ferguson and Simon Rock Levinson}, journal={Muscle & nerve}, year={1994}, volume={17 6}, pages={593-8} }