Sodium channel distribution within the rabbit atrioventricular node as analysed by confocal microscopy.

@article{Petrecca1997SodiumCD,
  title={Sodium channel distribution within the rabbit atrioventricular node as analysed by confocal microscopy.},
  author={Kevin Petrecca and F Amellal and Dale W Laird and Sidney A. Cohen and Alvin Shrier},
  journal={The Journal of physiology},
  year={1997},
  volume={501 ( Pt 2)},
  pages={263-74}
}
1. Paired 20 microns thick sections of fresh frozen tissue taken from the frontal plane of the rabbit atrioventricular (AV) nodal region were processed for histology and immunohistochemistry. Confocal microscopy was used to image the distribution of sodium channels using IgG (R12) developed against a highly conserved sequence in the interdomain 3-4 region of cloned sodium channels. 2. In ventricular and atrial cells, sodium channel immunofluorescence was localized to lateral membranes and T… CONTINUE READING
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