Sodium borohydride in carboxylic acid media: a phenomenal reduction system

@article{Gribble1998SodiumBI,
  title={Sodium borohydride in carboxylic acid media: a phenomenal reduction system},
  author={G. Gribble},
  journal={Chemical Society Reviews},
  year={1998},
  volume={27},
  pages={395-404}
}
  • G. Gribble
  • Published 1998
  • Chemistry
  • Chemical Society Reviews
  • The union of sodium borohydride and carboxylic acids has yielded an amazingly versatile and efficient set of reducing reagents. These acyloxyborohydride species reduce and N-alkylate indoles, quinolines, isoquinolines, related heterocycles, imines, enamines, oximes, enamides, and similar functional groups. They reduce amides and nitriles, aryl alcohols and ketones, aldehydes in the presence of ketones, and β-hydroxyketones to 1,3-diols stereoselectively. This reagent is also extraordinarily… CONTINUE READING
    181 Citations
    Phenylsilane as an effective desulfinylation reagent
    • 1
    • PDF

    References

    SHOWING 1-10 OF 32 REFERENCES