Sodium bicarbonate lowers intracranial pressure after traumatic brain injury.

@article{Bourdeaux2010SodiumBL,
  title={Sodium bicarbonate lowers intracranial pressure after traumatic brain injury.},
  author={Chris Paul Bourdeaux and Jules M Brown},
  journal={Neurocritical care},
  year={2010},
  volume={13 1},
  pages={24-8}
}
BACKGROUND Hypertonic saline is routinely used to treat rises in intracranial pressure (ICP) post-traumatic head injury. Repeated doses often cause a hyperchloremic metabolic acidosis. We investigated the efficacy of 8.4% sodium bicarbonate as an alternative method of lowering ICP without generating a metabolic acidosis. METHODS We prospectively studied 10 episodes of unprovoked ICP rise in 7 patients treated with 85 ml of 8.4% sodium bicarbonate in place of our usual 100 ml 5% saline. We… CONTINUE READING
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