Sodium and potassium permeability of membrane vesicles in a sarcolemma-enriched preparation from canine ventricle

@article{Schilling1984SodiumAP,
  title={Sodium and potassium permeability of membrane vesicles in a sarcolemma-enriched preparation from canine ventricle},
  author={William P. Schilling and Duane W. Schuil and Ervin E. Bagwell and George E. Lindenmayer},
  journal={The Journal of Membrane Biology},
  year={1984},
  volume={77},
  pages={101-114}
}
Vesicles in a highly enriched sarcolemma preparation from canine ventricle were found to develop membrane potentials in response to outwardly directed potassium and inwardly directed sodium concentration gradients. The magnitude of the potential measured by the fluorescent dye diS−C3-(5) suggested a sodium-to-potassium permeability ratio between 0.2 and 1.0 which is one to two orders of magnitude greater than values obtained for the myocardial cell. Radiotracer techniques were employed to… CONTINUE READING