Sodium Lauryl Sulfate-Induced Irritation in the Human Face: Regional and Age-Related Differences

@article{Marrakchi2006SodiumLS,
  title={Sodium Lauryl Sulfate-Induced Irritation in the Human Face: Regional and Age-Related Differences},
  author={S. Marrakchi and H. Maibach},
  journal={Skin Pharmacology and Physiology},
  year={2006},
  volume={19},
  pages={177 - 180}
}
The particular sensitivity of the human face to care products prompted us to study irritation induced by sodium lauryl sulfate (SLS) in its various regions. We examined regional and age-related differences, correlating basal transepidermal water loss (TEWL) and capacitance to SLS irritation. SLS (2% aq.) was applied under occlusion for 1 h to the forehead, cheek, nose, nasolabial and perioral areas, chin, neck and forearm to two groups of subjects – one with 10 subjects with an average age of… Expand
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