Sodium/myo-inositol cotransporter-1 is essential for the development and function of the peripheral nerves.

@article{Chau2005SodiummyoinositolCI,
  title={Sodium/myo-inositol cotransporter-1 is essential for the development and function of the peripheral nerves.},
  author={Jenny Fung Ling Chau and Moon Kyu Lee and Janice W. S. Law and Sookja K Chung and Stephen Sum Man Chung},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2005},
  volume={19 13},
  pages={1887-9}
}
Sodium/myo-inositol cotransporter-1 (SMIT-1) is one of the transporters responsible for importing myo-inositol (MI) into the cells. MI is a precursor for a family of signal transduction molecules, phosphatidylinositol, and its derivatives that regulates many cellular functions. SMIT-1 null mice died soon after birth due to respiratory failure, but neonatal lethality was prevented by prenatal maternal MI supplement. Although the lung air sacs were closed, lung development was not significantly… CONTINUE READING

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