Socio-Behavioral Characteristics of Children with Rubinstein-Taybi Syndrome

@article{Galra2009SocioBehavioralCO,
  title={Socio-Behavioral Characteristics of Children with Rubinstein-Taybi Syndrome},
  author={C{\'e}dric Gal{\'e}ra and Emmanuelle Taupiac and Sonia Fraisse and Sophie Naudion and Eva Toussaint and Caroline Rooryck-Thambo and Marie-Ange Delrue and Beno{\^i}t Arveiler and Didier Lacombe and Manuel Bouvard},
  journal={Journal of Autism and Developmental Disorders},
  year={2009},
  volume={39},
  pages={1252-1260}
}
Research regarding the behavioral aspects of children with Rubinstein-Taybi syndrome (RTS) has suggested some possible behavioral patterns including autistic features. Caregivers of 39 children (mean age = 8.4 years) with RTS (49% showing abnormality in CREBBP gene) and 39 children (mean age = 8.6 years) matched on developmental level, age and gender were administered the Child Behavior Checklist and the Children’s Social Behavior Questionnaire. Children with RTS did not exhibit higher… Expand
Age‐dependent change in behavioral feature in Rubinstein‐Taybi syndrome
TLDR
It is shown that the specific behavioral phenotypes of RTS change during adolescence, with anxiety, mood instability, and aggressive behavior emerging as patients age. Expand
Repetitive Behavior in Rubinstein–Taybi Syndrome: Parallels with Autism Spectrum Phenomenology
TLDR
A phenotypic profile of repetitive behavior was found in Rubinstein–Taybi syndrome and the majority of behaviors in RTS were not associated with social-communication deficits or degree of disability. Expand
Psychomotor, cognitive, and socio-emotional developmental profiles of children with Rubinstein-Taybi Syndrome and a severe intellectual disability
ABSTRACT Background: Rubinstein-Taybi syndrome (RSTS) is a multiple congenital anomaly syndrome characterised by several typical somatic characteristics and by developmental disabilities with variousExpand
The behavioural and cognitive phenotype of Rubinstein-Taybi syndrome
In a series of studies, repetitive behaviour, executive function development and the links between these constructs were explored in Rubinstein-Taybi syndrome (RTS). An overview of these constructsExpand
Developmental Profile and Diagnoses in Children Presenting with Motor Stereotypies
TLDR
Motor stereotypies in children with normal cognitive level represent a challenging diagnostic issue for which a finely tailored assessment is mandatory in order to define a precise developmental profile and careful and cautious use of standardized tests is warranted to avoid mis diagnosis. Expand
An Observational Study of Social Interaction Skills and Behaviors in Cornelia de Lange, Fragile X and Rubinstein-Taybi Syndromes
TLDR
Assessment of broader aspects of sociability in individuals with Cornelia de Lange (CdLS), fragile X (FXS) and Rubinstein-Taybi syndromes (RTS) and their association with autism characteristics and chronological age differed between groups, which may indicate divergence in the development and aetiology of different components of sociable across these groups. Expand
Rubinstein-Taybi syndrome : from behaviour to cognition
Examination of Autism Spectrum Disorder (ASD) phenomenology in genetic syndromes can aid our understanding of the aetiological pathways underpinning ASD. The current thesis directed attention to theExpand
Evaluation of Motor Skills in Children with Rubinstein–Taybi Syndrome
TLDR
This study demonstrates a reduction in the motor performance of RTS participants and a link between the level of intellectual disability and motor capacities. Expand
The development of early social cognitive skills in neurogenetic syndromes associated with autism: Cornelia de Lange, fragile X and Rubinstein–Taybi syndromes
TLDR
An underlying mechanism other than general cognitive delay may be disrupting early social cognitive development in children with CdLS, FXS and RTS. Expand
A Behavioural Assessment of Social Anxiety and Social Motivation in Fragile X, Cornelia de Lange and Rubinstein-Taybi Syndromes
TLDR
The effects of adult familiarity and nature of interaction on social anxiety and social motivation were investigated in individuals with fragile X, Cornelia de Lange and Rubinstein-Taybi syndromes compared to individuals with Down syndrome. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 41 REFERENCES
Psychological and speech studies in Rubinstein-Taybi syndrome.
TLDR
Comparable studies of other groups of persons with a specific syndrome are needed to determine whether the present findings are specific for Rubinstein-Taybi syndrome or may be found among persons with other syndromes. Expand
Psychopathology, GABA, and the Rubinstein-Taybi syndrome: a review and case study.
An adult female with congenital Rubinstein-Taybi syndrome (RTS) and severe mental retardation is described, who presented with symptoms of severe over-activity, short attention span, mood lability,Expand
Behavioral characteristics of three children with the broad thumb-hallux (Rubinstein-Taybi) syndrome.
TLDR
The pattern of R-T mutual resemblances and their differences from other clinic children logically suggest what may be the behavioral characteristics of children with the R- T syndrome. Expand
Behavioral characteristics of three children with the broad thumb-hallux (Rubinstein-Taybi) syndrome.
: Behavioral characteristics of three children with Broad Thumb-Hallux or Rubinstein-Taybi (R-T) syndrome were compared with those of a somewhat comparable clinic sample (N - 15) of children withExpand
The Children's Social Behavior Questionnaire for Milder Variants of PDD Problems: Evaluation of the Psychometric Characteristics
TLDR
Results show that the CSBQ has good psychometric qualities with respect to both reliability and validity, and that the autism group received the highest scores, followed by the PDDNOS group and the ADHD group. Expand
Emotional and behavioral problems in children and adolescents with and without intellectual disability.
TLDR
Elevated scale scores reflected differences between children with and without ID over a broad range of items, and not solely on items more likely to be related to developmental delay, which deserve special attention in the mental health care of children with ID. Expand
Behavioral and temperamental features of children with Costello syndrome
Costello syndrome (CS) is a rare genetic condition due to germline mutations in HRAS proto‐oncogene and characterized by increased birth weight, postnatal growth retardation, distinctive facialExpand
Rubinstein-Taybi syndrome: a natural history study.
TLDR
Individuals with Rubinstein-Taybi syndrome were found to have particular difficulty with expressive speech skills, and indexes for maladaptive behavior were calculated showing that approximately 10% of patients had significant behavior problems. Expand
Refinement of the Children’s Social Behavior Questionnaire (CSBQ): An Instrument that Describes the Diverse Problems Seen in Milder Forms of PDD
The objective of this study was to refine the Children’s Social Behavior Questionnaire (CSBQ), to reduce its length, and to verify its psychometric properties. The CSBQ is a questionnaire for parentsExpand
Rubinstein-Taybi syndrome and psychiatric disorders.
  • A. Levitas, C. Reid
  • Psychology, Medicine
  • Journal of intellectual disability research : JIDR
  • 1998
TLDR
The present authors suggest that the gene locus for RTS should be investigated for genes related to the regulation of these neurotransmitters, given the suspected relationship of these complications with the serotonergic and dopaminergic systems. Expand
...
1
2
3
4
5
...