Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress

@article{Heinrichs2003SocialSA,
  title={Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress},
  author={Markus Heinrichs and Thomas Baumgartner and Clemens Kirschbaum and Ulrike Ehlert},
  journal={Biological Psychiatry},
  year={2003},
  volume={54},
  pages={1389-1398}
}
BACKGROUND The presence of social support has been associated with decreased stress responsiveness. Recent animal studies suggest that the neuropeptide oxytocin is implicated both in prosocial behavior and in the central nervous control of neuroendocrine responses to stress. This study was designed to determine the effects of social support and oxytocin on cortisol, mood, and anxiety responses to psychosocial stress in humans. METHODS In a placebo-controlled, double-blind study, 37 healthy… Expand
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Intranasal oxytocin enhances stress-protective effects of social support in women with negative childhood experiences during a virtual Trier Social Stress Test
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Results may indicate that oxytocin is a neurobiological means to attain and benefit from social support under stressful circumstances, which may be particularly adaptive for women with a history of adversity. Expand
Adult attachment and social support interact to reduce psychological but not cortisol responses to stress.
TLDR
This first study on the interaction of adult attachment and social support in terms of psychological and endocrine stress responses concurs with previous studies suggesting an important protective role of attachment for psychological stress responsiveness, however, attachment did not directly moderate cortisol responses to acute stress. Expand
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