Social stress enhances IL-1beta and TNF-alpha production by Porphyromonas gingivalis lipopolysaccharide-stimulated CD11b+ cells.

@article{Bailey2009SocialSE,
  title={Social stress enhances IL-1beta and TNF-alpha production by Porphyromonas gingivalis lipopolysaccharide-stimulated CD11b+ cells.},
  author={Michael T. Bailey and Steven G Kinsey and David A. Padgett and John F Sheridan and Binnaz Leblebicioglu},
  journal={Physiology & behavior},
  year={2009},
  volume={98 3},
  pages={351-8}
}
Psychological stress is associated with an increased expression of markers of peripheral inflammation, and there is a growing literature describing a link between periodontal pathogens and systemic inflammation. The hypothesis of the present work is that exposing mice to the social stressor, called social disruption (SDR), would enhance the inflammatory response to lipopolysaccharide (LPS) derived from the oral pathogen, Porphyromonas gingivalis. Mice were exposed to SDR for 2h per day on 6… CONTINUE READING

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