Social stress and escalated drug self-administration in mice I. Alcohol and corticosterone

@article{Norman2014SocialSA,
  title={Social stress and escalated drug self-administration in mice I. Alcohol and corticosterone},
  author={K. Norman and Jacob A. Seiden and Jacob A. Klickstein and Xiao Han and Lara S. Hwa and Joseph F. DeBold and Klaus A. Miczek},
  journal={Psychopharmacology},
  year={2014},
  volume={232},
  pages={991-1001}
}
  • K. Norman, Jacob A. Seiden, +4 authors Klaus A. Miczek
  • Published 2014
  • Psychology, Medicine
  • Psychopharmacology
  • RationaleStress experiences have been shown to be a risk factor for alcohol abuse in humans; however, a reliable mouse model using episodic social stress has yet to be developed.ObjectivesThe current studies investigated the effects of mild and moderate social defeat protocols on plasma corticosterone, voluntary alcohol drinking, and motivation to drink alcohol.MethodsOutbred Carworth Farms Webster (CFW) mice were socially defeated for 10 days during which the intruder mouse underwent mild (15… CONTINUE READING
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    References

    SHOWING 1-10 OF 86 REFERENCES
    Persistent suppression of ethanol self-administration by brief social stress in rats and increased startle response as index of withdrawal
    • 108
    Social stress and escalated drug self-administration in mice II. Cocaine and dopamine in the nucleus accumbens
    • 29
    • Highly Influential
    Social defeat increases alcohol preference of C57BL/10 strain mice; effect prevented by a CCKB antagonist
    • 68
    Effects of unconditioned and conditioned social defeat on alcohol self-administration and reinstatement of alcohol seeking in rats
    • 79
    Short or continuous social stress: suppression of continuously available ethanol intake in subordinate rats
    • 55
    Social stress increases the acquisition of cocaine self-administration in male and female rats
    • 251
    A standardized protocol for repeated social defeat stress in mice
    • 642
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