Social regulation of leukocyte homeostasis: The role of glucocorticoid sensitivity

@article{Cole2008SocialRO,
  title={Social regulation of leukocyte homeostasis: The role of glucocorticoid sensitivity},
  author={Steve W. Cole},
  journal={Brain, Behavior, and Immunity},
  year={2008},
  volume={22},
  pages={1049-1055}
}
Recent small-scale genomics analyses suggest that physiologic regulation of pro-inflammatory gene expression by endogenous glucocorticoids may be compromised in individuals who experience chronic social isolation. The present study assessed the relationship between leukocyte distributional sensitivity to glucocorticoid regulation and subjective social isolation in a large population-based sample of older adults. Initial analyses confirmed that circulating neutrophil percentages were elevated… CONTINUE READING
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