Social neuroscience and health: neurophysiological mechanisms linking social ties with physical health

@article{Eisenberger2012SocialNA,
  title={Social neuroscience and health: neurophysiological mechanisms linking social ties with physical health},
  author={Naomi I. Eisenberger and Steve W. Cole},
  journal={Nature Neuroscience},
  year={2012},
  volume={15},
  pages={669-674}
}
Although considerable research has shown the importance of social connection for physical health, little is known about the higher-level neurocognitive processes that link experiences of social connection or disconnection with health-relevant physiological responses. Here we review the key physiological systems implicated in the link between social ties and health and the neural mechanisms that may translate social experiences into downstream health-relevant physiological responses… 

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References

SHOWING 1-10 OF 63 REFERENCES

Neural mechanisms of social risk for psychiatric disorders

existing evidence on the effects of common genetic risk factors in social neural pathways and the need for integrative approaches to identify the converging mechanisms of social environmental and genetic risk in brain are discussed.

Health Psychology : Developing Biologically Plausible Models Linking the Social World and Physical Health

Research over the past several decades has documented psychosocial influences on the development and progression of several major medical illnesses. The field is now increasingly focused on

Decreased ventral anterior cingulate cortex activity is associated with reduced social pain during emotional support

The results suggest that the ventral ACC underlies social pain, and that emotional support enhances prefrontal cortex activity, which in turn may lead to a weakened affective response.

The Neural Sociometer: Brain Mechanisms Underlying State Self-esteem

Results demonstrated that greater activity in rejection-related neural regions (dorsal ACC, anterior insula) and mentalizing regions was associated with lower-state self-esteem, and these results inform the understanding of the origin and nature of the authors' feelings about ourselves.

Perceived social isolation and cognition

Social rejection shares somatosensory representations with physical pain

It is demonstrated that when rejection is powerfully elicited—by having people who recently experienced an unwanted break-up view a photograph of their ex-partner as they think about being rejected—areas that support the sensory components of physical pain become active.
...