Social isolation stress during the third week of life has age-dependent effects on spatial learning in rats.

@article{Frisone2002SocialIS,
  title={Social isolation stress during the third week of life has age-dependent effects on spatial learning in rats.},
  author={Deborah F Frisone and Cheryl Anne Frye and Betty Zimmerberg},
  journal={Behavioural brain research},
  year={2002},
  volume={128 2},
  pages={153-60}
}
Despite extensive research on the relationship between acute stress and hippocampal function in adults, little is known about the short- and long-term effects of prolonged juvenile stress on learning, memory, and other hippocampal functions. This experiment investigated whether spatial learning would be altered in juvenile and adult rats previously exposed to a chronic stressor: 6 h of social isolation (SI) daily at 15-21 days of age. SI was found to increase circulating plasma levels of… CONTINUE READING

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