Social dominance in female monkeys: dopamine receptor function and cocaine reinforcement.

  title={Social dominance in female monkeys: dopamine receptor function and cocaine reinforcement.},
  author={Michael A. Nader and Susan H. Nader and Paul W. Czoty and Natallia V. Riddick and H. Donald Gage and Robert Wayne Gould and Brandi L Blaylock and Jay R. Kaplan and Pradeep K Garg and Huw M. L. Davies and Daniel Morton and Sudha Garg and Beth A. Reboussin},
  journal={Biological psychiatry},
  volume={72 5},
BACKGROUND Brain imaging and behavioral studies suggest an inverse relationship between dopamine (DA) D2/D3 receptors and vulnerability to cocaine abuse, although most research has used males. For example, male monkeys that become dominant in a social group have significant elevations in D2/D3 receptor availability and are less vulnerable to cocaine reinforcement. METHODS DA D2/D3 receptor availability was assessed in female cynomolgus monkeys (n = 16) with positron emission tomography (PET… CONTINUE READING
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