Social defeat increases alcohol preference of C57BL/10 strain mice; effect prevented by a CCKB antagonist

@article{Croft2005SocialDI,
  title={Social defeat increases alcohol preference of C57BL/10 strain mice; effect prevented by a CCKB antagonist},
  author={Adam Paul Croft and S. P. Brooks and Jon Cole and Hilary J. Little},
  journal={Psychopharmacology},
  year={2005},
  volume={183},
  pages={163-170}
}
In humans, social stress over long and short term can increase alcohol consumption, but the mechanisms involved are not understood. This study was conducted to examine the effects of social defeat, using the resident/intruder paradigm, on the alcohol preference of “low alcohol drinking” individuals in a colony of C57BL/10 strain mice and the effects of two anxiolytic drugs. Alcohol preference, in a two-bottle choice (8% v/v alcohol or water), was measured, in separate experiments, after either… CONTINUE READING

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