Social defeat as a stressor in humans

  title={Social defeat as a stressor in humans},
  author={Kaj Bj{\"o}rkqvist},
  journal={Physiology \& Behavior},

From fighting animals to the biosocial mechanisms of the human mind: A comparison of Selten’s social defeat and Mead’s symbolic interaction

Social defeat is a psychiatric theory accounting for the role of social environment in the aetiology of psychosis via the mechanism of stress. Social defeat stems from animal studies of stress,

Animal models of social stress: the dark side of social interactions

It appears that both nonapeptides balance the relative strength of the stress response, and simultaneously predispose the animal to positive or negative social interactions.

The socially stressed heart. Insights from studies in rodents

Dominance relationships in Syrian hamsters modulate neuroendocrine and behavioral responses to social stress

It is indicated that dominant social status does not alter stress-induced activity of the extended hypothalamic-pituitary-adrenal (HPA) axis, which suggests that the ability of dominants to cope with social defeat stress is not associated with changes in their neuroendocrine stress response.

Social stress contagion in rats: Behavioural, autonomic and neuroendocrine correlates

Social defeat stress: Mechanisms underlying the increase in rewarding effects of drugs of abuse

The most characteristic results of the short‐ and long‐term consequences of social defeat stress on the rewarding effects of drugs of abuse such as psychostimulants and alcohol are described and the neurobiological mechanisms underlying these effects are assessed.

Regulation of defeat-induced social avoidance by medial amygdala DRD1 in male and female prairie voles

Findings provide the prairie vole as a model of social defeat in both sexes, and implicate the MeA in avoidance of unfamiliar conspecifics after a distressing social encounter.



Using ethological principles to study psychosocial influences on coronary atherosclerosis in monkeys.

Studies with male cynomolgus monkeys suggest that atherosclerosis is potentiated among individuals that are habitually successful in their aggressive encounters with social strangers, thereby retaining dominant social status in an unstable environment, providing clear support for the hypothesis that psychosocial factors influence disease pathogenesis via neuroendocrine mediation.

Chronic Social Stress, Social Status, and Susceptibility to Upper Respiratory Infections in Nonhuman Primates

Although the social instability manipulation was associated with increased agonistic behavior as indicated by minor injuries and elevated norepinephrine responses to social reorganizations, the manipulation did not influence the probability of being infected by the virus.

The temporal dynamics of the stress response

Aggression among university employees

Harassment among university employees (n = 338; 162 males, 176 females) was investigated by help of the Work Harassment Scale (WHS), developed for the study. Nineteen cases of severe victimization by

Social stress, autonomic neural activation, and cardiac activity in rats

Correlation between anxiety and serum prolactin in humans.