Social and structural housing conditions influence the development of a depressive-like phenotype in the learned helplessness paradigm in male mice.

@article{Chourbaji2005SocialAS,
  title={Social and structural housing conditions influence the development of a depressive-like phenotype in the learned helplessness paradigm in male mice.},
  author={Sabine Chourbaji and Christiane Zacher and Carles Sanchis-Segura and Rainer Spanagel and Peter Gass},
  journal={Behavioural brain research},
  year={2005},
  volume={164 1},
  pages={100-6}
}
Structural and social factors are known to play a crucial role in the pathogenesis of depression. Since animal models of depression are a major tool to gain insights into the mechanisms involved in the pathophysiology of this disease it is important not only to exploit but also to be aware of factors that may affect these models. As housing represents a fundamental external factor, which is controversially debated to affect the animals' emotionality, this study aimed to investigate the impact… CONTINUE READING

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