Social Play Behavior in Adolescent Rats is Mediated by Functional Activity in Medial Prefrontal Cortex and Striatum

@article{Kerkhof2013SocialPB,
  title={Social Play Behavior in Adolescent Rats is Mediated by Functional Activity in Medial Prefrontal Cortex and Striatum},
  author={Linda W. M. van Kerkhof and Ruth Damsteegt and Viviana Trezza and Pieter Voorn and Louk J. M. J. Vanderschuren},
  journal={Neuropsychopharmacology},
  year={2013},
  volume={38},
  pages={1899-1909}
}
Social play behavior is a characteristic, vigorous form of social interaction in young mammals. It is highly rewarding and thought to be of major importance for social and cognitive development. The neural substrates of social play are incompletely understood, but there is evidence to support a role for the prefrontal cortex (PFC) and striatum in this behavior. Using pharmacological inactivation methods, ie, infusions of GABA receptor agonists (baclofen and muscimol; B&M) or the AMPA/kainate… CONTINUE READING
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