Sociability and motor functions in Shank1 mutant mice

@article{Silverman2011SociabilityAM,
  title={Sociability and motor functions in Shank1 mutant mice},
  author={Jill L Silverman and Sarah M. Turner and Charlotte L Barkan and Seda S. Tolu and Jacqueline N. Crawley},
  journal={Brain Research},
  year={2011},
  volume={1380},
  pages={120-137}
}
Autism is a neurodevelopmental disorder characterized by aberrant reciprocal social interactions, impaired communication, and repetitive behaviors. While the etiology remains unclear, strong evidence exists for a genetic component, and several synaptic genes have been implicated. SHANK genes encode a family of synaptic scaffolding proteins located postsynaptically on excitatory synapses. Mutations in SHANK genes have been detected in several autistic individuals. To understand the consequences… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 100 CITATIONS, ESTIMATED 50% COVERAGE

Neurodevelopmental synaptopathies: Insights from behaviour in rodent models of synapse gene mutations

  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • 2017
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Behavioral phenotypes of genetic mouse models of autism.

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Early communication deficits in the Shank1 knockout mouse model for autism spectrum disorder: Developmental aspects and effects of social context.

  • Autism research : official journal of the International Society for Autism Research
  • 2016
VIEW 10 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

Genetic and non-genetic animal models for autism spectrum disorders (ASD).

  • Reproductive toxicology
  • 2016
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2012
VIEW 4 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2010
2019

CITATION STATISTICS

  • 12 Highly Influenced Citations

  • Averaged 9 Citations per year from 2017 through 2019