SoDA: implementation of a 3D alignment algorithm for inference of antigen receptor recombinations


MOTIVATION The antigen receptors of adaptive immunity-T-cell receptors and immunoglobulins-are encoded by genes assembled stochastically from combinatorial libraries of gene segments. Immunoglobulin genes then experience further diversification through hypermutation. Analysis of the somatic genetics of the immune response depends explicitly on inference of… (More)
DOI: 10.1093/bioinformatics/btk004