SnpFilt: A pipeline for reference-free assembly-based identification of SNPs in bacterial genomes

Abstract

De novo assembly of bacterial genomes from next-generation sequencing (NGS) data allows a reference-free discovery of single nucleotide polymorphisms (SNP). However, substantial rates of errors in genomes assembled by this approach remain a major barrier for the reference-free analysis of genome variations in medically important bacteria. The aim of this… (More)
DOI: 10.1016/j.compbiolchem.2016.09.004
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