Snorkeling of lysine side chains in transmembrane helices: how easy can it get?

Abstract

Transmembrane segments of proteins are often flanked by lysine residues. The side chains of these residues may snorkel, i.e. they may bury themselves with their aliphatic part in the hydrophobic region of the lipid bilayer, while positioning the charged amino group in the more polar interface. Here we estimate the free energy cost of snorkeling from… (More)

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Cite this paper

@article{Strandberg2003SnorkelingOL, title={Snorkeling of lysine side chains in transmembrane helices: how easy can it get?}, author={Erik Strandberg and J. Antoinette Killian}, journal={FEBS letters}, year={2003}, volume={544 1-3}, pages={69-73} }