SnoVectors for nuclear expression of RNA

Abstract

Many long noncoding RNAs (lncRNAs) are constrained to the nucleus to exert their functions. However, commonly used vectors that were designed to express mRNAs have not been optimized for the study of nuclear RNAs. We reported recently that sno-lncRNAs are not capped or polyadenylated but rather are terminated on each end by snoRNAs and their associated… (More)
DOI: 10.1093/nar/gku1050

Topics

6 Figures and Tables