SnoN as a key regulator of the high glucose-induced epithelial-mesenchymal transition in cells of the proximal tubule.

@article{Liu2012SnoNAA,
  title={SnoN as a key regulator of the high glucose-induced epithelial-mesenchymal transition in cells of the proximal tubule.},
  author={Ruixia Liu and Yuanyuan Wang and Ying Xiao and Mingjun Shi and Guozhong Zhang and Bing Guo},
  journal={Kidney & blood pressure research},
  year={2012},
  volume={35 6},
  pages={517-28}
}
BACKGROUND/AIMS Ski-related protein N (SnoN) suppression is essential to transforming growth factor-β1 induction and the epithelial-mesenchymal transition (EMT) in several cancer cells. The role of SnoN in diabetic nephropathy is unknown. We aimed to determine the role of SnoN in the EMT of proximal tubule cells (PTCs) maintained under high glucose conditions. METHODS Immunohistochemistry, immunocytochemistry, Western blotting, small interfering RNA gene silencing, viral transduction and RT… CONTINUE READING

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Suramin inhibits renal fibrosis in chronic kidney disease.

Journal of the American Society of Nephrology : JASN • 2011

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