Snakeskin, a membrane protein associated with smooth septate junctions, is required for intestinal barrier function in Drosophila.

@article{Yanagihashi2012SnakeskinAM,
  title={Snakeskin, a membrane protein associated with smooth septate junctions, is required for intestinal barrier function in Drosophila.},
  author={Yuichi Yanagihashi and Tadao Usui and Yasushi Izumi and Shigenobu Yonemura and Motoyuki Sumida and Shoichiro Tsukita and Tadashi Uemura and Mikio Furuse},
  journal={Journal of cell science},
  year={2012},
  volume={125 Pt 8},
  pages={1980-90}
}
Septate junctions (SJs) are the membrane specializations observed between epithelial cells in invertebrates. SJs play a crucial role in epithelial barrier function by restricting the free diffusion of solutes through the intercellular space. In arthropod species, two morphologically different types of SJs have been described: pleated septate junctions (pSJs) and smooth septate junctions (sSJs), which are specific to ectodermal and endodermal epithelia, respectively. In contrast to the recent… CONTINUE READING
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