Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia

@article{FernndezCulma2014SnakeVO,
  title={Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia},
  author={Maritza Fern{\'a}ndez Culma and Jaime Andr{\'e}s Perea{\~n}ez and Vitelbina N{\'u}{\~n}ez Rangel and Bruno Lomonte},
  journal={PeerJ},
  year={2014},
  volume={2}
}
Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized. In the present work, the protein composition of this venom was profiled using the ‘snake venomics’ analytical strategy. Decomplexation of the crude venom by RP-HPLC and SDS-PAGE, followed by tandem mass spectrometry of tryptic digests, showed that it consists of proteins assigned to at least nine snake toxin families. Metalloproteinases are… 
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  • C. Cañas, A. Vallejo
  • Medicine
    Toxicon : official journal of the International Society on Toxinology
  • 2016
TLDR
Two patients bitten by B. punctatus are described, whose most relevant clinical feature was the development of a severe coagulopathy with few local manifestations at the site of the bite.
TOXINOLOGY IN COLOMBIA: CONTRIBUTIONS OF OPHIDISM/SCORPIONISM PROGRAM AND OTHER RESEARCH GROUPS TOXINOLOGÍA EN COLOMBIA: CONTRIBUCIONES DEL PROGRAMA DE OFIDISMO/ ESCORPIONISMO Y DE OTROS GRUPOS DE INVESTIGACIÓN
Background: Toxinology is a sub-field of toxicology dedicated to studying toxins produced by animals, plants and, microorganisms. In Colombia, during the last thirty years, this area has been mainly
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