Snake venom proteases affecting hemostasis and thrombosis.

@article{Matsui2000SnakeVP,
  title={Snake venom proteases affecting hemostasis and thrombosis.},
  author={Taei Matsui and Yoshihiro Fujimura and Koiti Titani},
  journal={Biochimica et biophysica acta},
  year={2000},
  volume={1477 1-2},
  pages={146-56}
}
The structure and function of snake venom proteases are briefly reviewed by putting the focus on their effects on hemostasis and thrombosis and comparing with their mammalian counterparts. Up to date, more than 150 different proteases have been isolated and about one third of them structurally characterized. Those proteases are classified into serine proteases and metalloproteinases. A number of the serine proteases show fibrin(ogen)olytic (thrombin-like) activities, which are not susceptible… CONTINUE READING

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Novel venom gene discovery in the platypus

View 8 Excerpts
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References

Publications referenced by this paper.
Showing 1-10 of 90 references

Puri¢cation and characterization of bothrombin

S. Nishida, Y. Fujimura, +8 authors H. Fukui
a ¢brinogen-clotting serine protease from the venom of Bothrops jararaca, Biochemistry 33 • 1994
View 5 Excerpts
Highly Influenced

Structure and function of snake venom metalloproteinase family

S. Iwanaga, H. Takeya
in: K. Imahori, F. Sakiyama (Eds.), Methods in Protein Sequence Analysis, Plenum Press, New York • 1993
View 9 Excerpts
Highly Influenced

Puri¢cation

S.M.T. Serrano, R. Mentele, C.A.M. Sampio, E. Fink
characterization, and amino acid sequence of a serine proteinase, PA-BJ, with platelet-aggregating activity from the venom of Bothrops jararaca, Biochemistry 34 • 1995
View 6 Excerpts
Highly Influenced

Snake venom metalloendopeptidases: reprolysins.

Methods in enzymology • 1995
View 5 Excerpts
Highly Influenced

Molecular cloning and sequence analysis of the cDNA for ancrod

L.-C. Au, S.-B. Liu, +3 authors C.-M. Shih
a thrombin-like enzyme from the venom of Calloselasma rhodostoma, Biochem. J. 294 • 1993
View 8 Excerpts
Highly Influenced

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