Snake venom Lys49 myotoxins: From phospholipases A(2) to non-enzymatic membrane disruptors.

@article{Lomonte2012SnakeVL,
  title={Snake venom Lys49 myotoxins: From phospholipases A(2) to non-enzymatic membrane disruptors.},
  author={Bruno Lomonte and Jos{\'e} David Rosales Rangel},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2012},
  volume={60 4},
  pages={520-30}
}
Snake venoms often contain toxins that cause a rapid necrosis of skeletal muscle fibers, referred to as myotoxins. The most common among them are phospholipases A(2) (PLA(2)s), enzymes that have two independent evolutionary origins in snake venoms. Within the group II PLA(2)s found in viperid venoms, a particular subgroup emerged, in which the otherwise… CONTINUE READING