Smooth muscle signalling pathways in health and disease

  title={Smooth muscle signalling pathways in health and disease},
  author={Hak Rim Kim and Sarah D Appel and Susanne Vetterkind and S S Gangopadhyay and Kathleen G Morgan},
  booktitle={Journal of cellular and molecular medicine},
Smooth muscle contractile activity is a major regulator of function of the vascular system, respiratory system, gastrointestinal system and the genitourinary systems. Malfunction of contractility in these systems leads to a host of clinical disorders, and yet, we still have major gaps in our understanding of the molecular mechanisms by which contractility of the differentiated smooth muscle cell is regulated. This review will summarize recent advances in the molecular understanding of the… CONTINUE READING