Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome

@article{Vickaryous2008SmoothmuscleMM,
  title={Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome},
  author={Nicola Vickaryous and Guadalupe M Polanco-Echeverry and Steve Morrow and Nirosha Suraweera and H. W. Thomas and Ian P. M. Tomlinson and Andrew Silver},
  journal={British Journal of Cancer},
  year={2008},
  volume={99},
  pages={1726 - 1728}
}
We examined adenomas and cancers from hereditary non-polyposis colorectal cancer (HNPCC) syndrome patients for the presence of frameshift mutations in the smooth-muscle myosin gene, MYH11. Our results show that mutations in MYH11 occur more frequently in cancers than adenomas (P=0.008) and are dependent on microsatellite instability (MSI+). 

From This Paper

Figures, tables, and topics from this paper.
6 Citations
11 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 11 references

Lindbolm A (2007) Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics

  • K Lagerstedt Robinson, T Liu, +9 authors M Nilbert
  • J Natl Cancer Inst 99:
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…