Smooth muscle gamma-actin promoter regulation by RhoA and serum response factor signaling.

@article{Carson2003SmoothMG,
  title={Smooth muscle gamma-actin promoter regulation by RhoA and serum response factor signaling.},
  author={James A Carson and Donald E Culberson and Raymond W. Thompson and Rebecca A Fillmore and Warren Zimmer},
  journal={Biochimica et biophysica acta},
  year={2003},
  volume={1628 2},
  pages={133-9}
}
Smooth muscle gamma-actin (SMGA) is both an early marker of smooth muscle cell differentiation, which demonstrates an expression pattern restricted to smooth muscle and the post meiotic spermatocyte. Serum response factor (SRF) DNA-binding is an important regulator of muscle differentiation, including SMGA expression during smooth muscle cell differentiation. RhoA, a low molecular weight GTPase protein, can regulate cardiac, skeletal, and smooth muscle differentiation through SRF-dependent… CONTINUE READING

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