Smooth muscle contraction as a model to study the mediator role of endogenous lipoxygenase products of arachidonic acid.

@article{Ritchie1984SmoothMC,
  title={Smooth muscle contraction as a model to study the mediator role of endogenous lipoxygenase products of arachidonic acid.},
  author={David M. Ritchie and Dr. W. Hahn and J L Mcguire},
  journal={Life sciences},
  year={1984},
  volume={34 6},
  pages={
          509-13
        }
}
In the lung, the contraction of smooth muscle, or bronchospasm, is generally caused by an immunologic insult resulting in mast cell degranulation and the release of histamine, slow reacting substances, and other mediators of inflammation (1). Although the immediate response is bronchospasm, continued activation of this sequence of events results in a chronic inflammatory disease. In the uterus, numerous conditions can result in smooth muscle contraction. One major pathophysiological syndrome… CONTINUE READING