Smooth Muscle Lineage Diversity in the Chick Embryo

  title={Smooth Muscle Lineage Diversity in the Chick Embryo},
  author={Topouzis and Majesky},
  journal={Developmental biology},
  volume={178 2},
Lineage analysis studies in the avian embryo have identified two types of smooth muscle cells (SMCs) in the tunica media of large elastic arteries; one that originates within the cardiac neural crest and is ectoderm in origin (Ect) and another that arises from local mesenchyme of mesodermal origin (Mes). To determine if differences in primary embryonic lineage can give rise to SMCs with stable differences in growth and differentiation properties, we isolated Ect and Mes SMCs from the Day 14… CONTINUE READING
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