Smoldering (asymptomatic) multiple myeloma: current diagnostic criteria, new predictors of outcome, and follow-up recommendations.

@article{Blad2010SmolderingM,
  title={Smoldering (asymptomatic) multiple myeloma: current diagnostic criteria, new predictors of outcome, and follow-up recommendations.},
  author={Joan Blad{\'e} and Meletios Α. Dimopoulos and Laura Rosi{\~n}ol and S Vincent Rajkumar and Robert A Kyle},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2010},
  volume={28 4},
  pages={690-7}
}
PURPOSE To provide an overview on smoldering (asymptomatic) multiple myeloma (SMM) including current diagnostic criteria, predictors of progression, pattern of progression, and outcome. DESIGN A comprehensive review of the literature on risk factors for progression, treatment attempts to delay progression and outcome in patients with SMM. RESULTS The risk factors for progression of SMM include: plasma cell mass including M-protein size and percentage of bone marrow clonal plasma cells (BMPC… CONTINUE READING